Horphag Research Europe Ltd (Geneva Branch)

Over 40 years of research has been dedicated by Horphag Research to establish the safety, efficacy and quality of Pycnogenol®, a natural extract of French maritime pine bark.

Pycnogenol® is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France and is found to contain a unique combination of procyanidins, bioflavonoids and phenolic acids, which offer extensive natural health benefits.

The extract has been widely studied for the past 40 years and has 350 published studies and review articles ensuring its safety and efficacy, with more than 135 clinical trials, and 10'000 subjects tested. Today, Pycnogenol® is available in 700 dietary supplements, multi-vitamins, cosmetics and health products worldwide.

Pycnogenol® is a powerful antioxidant, selectively binds to collagen and elastin, is a natural anti-inflammatory, and aids in the production of endothelial nitric oxide which helps to vasodilate blood vessels.

Among others, applications include cardiovascular health, skin care, eye health, joint health, cognitive health, women's health and menopause.

Horphag Research is the exclusive worldwide supplier of Pycnogenol® and the extract is ISO, GMP certified, and GRAS-approved. For more information, visit www.pycnogenol.com

Our Products

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Cognitive Function

Pycnogenol® & Cognitive Health

Research has shown Pycnogenol® French mariti...

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Eye Health and Vision

Pycnogenol® for Eyes & Vision

The natural ageing process affects the sharpn...

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Heart and Circulatory Health

Pycnogenol® for Heart Health

Pycnogenol® French maritime pine bark extrac...

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Joint Support

Pycnogenol® for Joint Health

More mobility, more flexibility, less pain, l...

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Skin Care and Beauty

Pycnogenol® for Skin Care

Your skin is your first line of defense again...

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Sports Nutrition

Pycnogenol® for Sports

Physical exercise is important to overall hea...

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Cognitive Function

Pycnogenol® & Cognitive Health

Research has shown Pycnogenol® French maritime pine bark extract improves cognitive function. Studies reveal Pycnogenol® improve both numerical and spatial working memory using a computerized testing system. Everyone may face difficulties dealing with nowadays lifestyle and increasing stress. As consequences, we may experience fatigue, anxiety, inability to concentrate and memory problems, among others. Pycnogenol® was found to improve memory and test scores in college students. This new clinical trial has shown Pycnogenol® to improve mental performance and decrease test anxiety by 17 %. Several recent research studies on Pycnogenol® studied the extract's effects on Attention Deficit Disorders including ADHD, and shown to reduce symptoms in children.

> Product document : Pycnogenol® - Cognitive Health

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Eye Health and Vision

Pycnogenol® for Eyes & Vision

The natural ageing process affects the sharpness of vision, everyone experiences decreased accommodation of the lens to see clearly at near at higher age. Five clinical studies with more than 1200 participants have demonstrated that Pycnogenol® improves the vascular system of the eyes to preserve healthy eyesight.

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Heart and Circulatory Health

Pycnogenol® for Heart Health

Pycnogenol® French maritime pine bark extract helps maintain a healthy cardiovascular system. Pycnogenol® French maritime pine bark extract may significantly contribute to the improvement of some risk factors, with the normalisation of blood pressure and platelet function, improvement of blood lipids as well as blood sugar values. An important number of clinical studies demonstrate the efficacy of Pycnogenol® for keeping cardiovascular health problems at bay. Research has found that Pycnogenol® helps individuals maintain healthy circulation by increasing vasodialation of blood vessels, thus improving blood flow. Pycnogenol® helps make blood platelets less «sticky», helping to reduce blood clots. Studies demonstrate that Pycnogenol® is a natural option for maintaining healthy cholesterol levels.

> Product document : Pycnogenol® for Circulation

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Joint Support

Pycnogenol® for Joint Health

More mobility, more flexibility, less pain, less drug. In various studies, Pycnogenol® French maritime pine bark extract demonstrated its ability to promote joint mobility and flexibility and naturally relieve the aching. It was also shown that after supplementing with Pycnogenol®, joints were more flexible and less medication was required. In addition Pycnogenol® has been found to lower inflammatory markers of joint soreness. Consumption of Pycnogenol® was shown to limit the activation of the pro-inflammatory «master switch» NF-kB by 15.8%. This «master switch» commands the mobilization of all proinflammatory molecules, which play a destructive role in arthritis.

> Product document : Pycnogenol® for Joint Health

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Skin Care and Beauty

Pycnogenol® for Skin Care

Your skin is your first line of defense against the daily rigors of life. Pycnogenol® helps your skin rebuild elasticity, essential for smooth and youthful looking skin. Pycnogenol’s® skin care benefits help protect the skin inside and out. Pycnogenol® French maritime pine bark extract is widely used in topical and oral applications for various dermatological indications. A unique combination of pharmacological functions of Pycnogenol® provides an unmatched variety of health benefits for skin health. Pycnogenol® binds and protects collagen and elastin Pycnogenol® protects elastic tissue proteins and stimulates genesis of new collagen and hyaluronic acid in human skin

> Product document : Pycnogenol® for Skin Care

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Sports Nutrition

Pycnogenol® for Sports

Physical exercise is important to overall health and at the same time increases our body’s need for oxygen. Research indicates Pycnogenol® may play an important role with physical activity because it was shown to aid the body in producing nitric oxide (NO), thus enhancing blood microcirculation and improving blood flow to the muscles. This helps the body achieve peak muscle performance and speeds recovery after exercise, which may result in reduction of muscular aches in both athletes and healthy individuals. Pycnogenol® stimulates the enzyme “endothelial nitric oxide synthase” (eNOS) for enhanced generation of NO from the precursor molecule L-arginine.

> Product document : Pycnogenol® for Sports

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